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Susan A Charman Selected Research

MMV390048

1/2018UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
1/2017Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

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Susan A Charman Research Topics

Disease

37Malaria
04/2022 - 08/2004
12Neoplasms (Cancer)
12/2021 - 08/2009
7Chagas Disease (American Trypanosomiasis)
12/2020 - 05/2012
7Infections
01/2019 - 05/2014
5Parasitemia
01/2021 - 09/2012
3Falciparum Malaria (Plasmodium falciparum Malaria)
01/2017 - 07/2006
2Drug-Related Side Effects and Adverse Reactions
12/2021 - 09/2015
2Parkinson Disease (Parkinson's Disease)
09/2021 - 01/2017
2Autoimmune Diseases (Autoimmune Disease)
08/2020 - 06/2014
1Hypoxia (Hypoxemia)
01/2022
1COVID-19
01/2022
1Tuberculosis (Tuberculoses)
12/2021
1Breast Neoplasms (Breast Cancer)
12/2021
1Visceral Leishmaniasis (Kala Azar)
12/2020
1Neglected Diseases
10/2020
1Schistosomiasis (Bilharziasis)
10/2020
1Neoplasm Metastasis (Metastasis)
01/2019
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/2018
1Lymphoma (Lymphomas)
01/2018
1Hepatocellular Carcinoma (Hepatoma)
01/2018
1Trypanosomiasis
11/2016
1Persistent Infection
10/2016
1Body Weight (Weight, Body)
09/2015

Drug/Important Bio-Agent (IBA)

28Pharmaceutical PreparationsIBA
04/2022 - 04/2010
17Antimalarials (Antimalarial Agents)IBA
11/2021 - 08/2004
8EnzymesIBA
01/2020 - 06/2012
61,2,4-trioxaneIBA
01/2021 - 03/2011
6Dihydroorotate DehydrogenaseIBA
01/2021 - 06/2014
6Biological ProductsIBA
12/2019 - 02/2010
5DSM265IBA
01/2021 - 07/2015
5artemisinin (artemisinine)IBA
01/2019 - 08/2004
4Carbonic Anhydrases (Carbonic Anhydrase)IBA
12/2013 - 10/2009
3Heme (Haem)IBA
11/2021 - 08/2004
3IronIBA
09/2021 - 01/2017
3pyrimidineIBA
01/2020 - 07/2015
3PeroxidesIBA
01/2020 - 07/2006
3Proteins (Proteins, Gene)FDA Link
01/2020 - 01/2015
3benzonidazole (benznidazole)IBA
10/2016 - 09/2012
3ProdrugsIBA
09/2015 - 09/2011
3SulfonamidesIBA
12/2013 - 10/2009
3IsoenzymesIBA
06/2012 - 10/2009
2alpha-SynucleinIBA
09/2021 - 01/2017
28-hydroxyquinazolin-4(3H)-oneIBA
09/2021 - 01/2017
2ArtesunateIBA
01/2019 - 08/2004
2MMV390048IBA
01/2018 - 01/2017
2alpha-aminopyridineIBA
01/2018 - 01/2017
2NifurtimoxIBA
10/2016 - 01/2015
2SulfonesIBA
10/2016 - 08/2014
2fexinidazoleIBA
10/2016 - 08/2014
26- Chloro- 7- methoxy- 2- methyl- 3- (4- (4- (trifluoromethoxy)phenoxy)phenyl)quinolin- 4(1H)- oneIBA
09/2015 - 03/2013
2QuinolonesIBA
05/2014 - 09/2012
2fenarimolIBA
12/2013 - 05/2012
2SterolsIBA
11/2013 - 09/2012
2Tubulin ModulatorsIBA
09/2011 - 08/2009
2CYT997IBA
11/2009 - 08/2009
1Antiviral Agents (Antivirals)IBA
01/2022
1Oxygen (Dioxygen)IBA
01/2022
1Anti-Bacterial Agents (Antibiotics)IBA
01/2022
1Isoniazid (Ftivazide)FDA LinkGeneric
12/2021
1Complement System Proteins (Complement)IBA
12/2021
1taxaneIBA
12/2021
1DiureticsIBA
01/2021
1Plasminogen Activators (Plasminogen Activator)IBA
01/2021
1TriazinesIBA
01/2021
15-(N,N-hexamethylene)amilorideIBA
01/2021
1Amiloride (Midamor)FDA LinkGeneric
01/2021
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
01/2021
1pretomanidIBA
12/2020
1NitroimidazolesIBA
12/2020
1Praziquantel (Biltricide)FDA Link
10/2020
1AntigensIBA
08/2020
1artefenomelIBA
01/2020
1arterolaneIBA
01/2020
1Lysine AcetyltransferasesIBA
01/2020
1PyrrolesIBA
01/2020
1CarbonIBA
12/2019
1ZincIBA
01/2019
1CD13 Antigens (Alanine Aminopeptidase)IBA
01/2019
1AminopeptidasesIBA
01/2019
1proguanil drug combination atovaquone (malarone)FDA Link
11/2018
12- Fluoro- N'- (3- fluoro- 5- (pyridin- 2- yl)benzoyl)benzenesulfonohydrazideIBA
01/2018
11-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)IBA
01/2018
12-(phenylsulfonyl)hydrazide 4-fluoro-5-methyl- (1,1'-Biphenyl)-3-carboxylic acidIBA
01/2018
1LigandsIBA
01/2017
12-aminopyrazineIBA
11/2016
1Mefloquine (Lariam)FDA LinkGeneric
11/2015
1Drug CombinationsIBA
07/2015
1Guanosine Triphosphate (GTP)IBA
01/2015
1Peptide Elongation Factor 2 (EF-2)IBA
01/2015
1DDD107498IBA
01/2015
1Messenger RNA (mRNA)IBA
01/2015
1SJ733IBA
12/2014
1sulfoxideIBA
08/2014
1Atovaquone (Mepron)FDA Link
05/2014
1Chloroquine (Aralen)FDA LinkGeneric
05/2014
1thiaplakortone AIBA
02/2014

Therapy/Procedure

7Therapeutics
12/2021 - 06/2011
3Drug Therapy (Chemotherapy)
12/2021 - 08/2004
3Oral Administration
01/2019 - 08/2014
1Duration of Therapy
10/2016